Many cases present unexpectedly at laparoscopy or laparotomy, or may be suspected at cross-sectional imaging during the investigation, or staging, of another pathological entity. Classically it is characterized by diffuse intra-abdominal gelatinous collections (jelly belly) with mucinous implants on peritoneal surfaces and the omentum. This is because pseudomyxoma peritonei is very rare.Pseudomyxoma peritonei (PMP) is an uncommon clinical entity with an estimated incidence of one to two per million per year. There are 2 designated UK specialist treatment centres. They recommend that people with PMP have treatment in a specialist centre. The guidance is on cytoreductive surgery with intraperitoneal chemotherapy. The National Institute for Health and Care Excellence (NICE) has produced guidance for PMP. Specialist centres for pseudomyxoma peritonei There hasn't yet been enough research into the benefits of systemic treatment for PMP. They will only suggest chemotherapy if your cancer is growing quickly or causing symptoms. If your cancer is slow growing, the doctor might suggest that they monitor you. It is important that you discuss the pros and cons of having treatment with your specialist. You might have either mitomycin C into a vein with or without capecitabine as tablets. CT scans show your cancer is growing quickly.You are more likely to have chemotherapy if: You might have chemotherapy if you can’t have surgery. Because of this, you might have debulking surgery more than once. Unless the surgeon can remove the whole cancer, it's very likely to come back. The surgeon might remove your womb and ovaries if you are a woman. It won’t cure PMP but might ease your symptoms. It could also mean that you can then have cytoreductive surgery with HIPEC.ĭebulking surgery might mean removing part of your bowel. It does not remove the cancer completely.ĭebulking surgery helps to make a diagnosis and get samples of the tumour. Read more general information about having surgeryĭebulking surgery aims to remove as much of the cancer as possible.About half of these people only need the stoma for 3 to 6 months, after which the bowel is put back together. A stoma is where the bowel is brought out to the surface of the tummy. About 20 out of 100 patients (20%) need a stoma after surgery. This might be less in some treatment centres. It can be at least 6 months before you are fully active again and able to work.Ībout 30 out of every 100 people (30%) have complications after treatment. It takes a long time to be able to recover from this operation. Some people may also need a blood transfusion after the operation. You’re likely to be in hospital for 2 to 3 weeks. feeding through a drip into a vein (intravenous), also called parenteral nutrition (PN) for about 2 weeks.a nasogastric tube (tube down your nose into your stomach to stop you being sick).an epidural (tube in the spine for pain relief).You might be in intensive care or a high dependency unit for 24 to 48 hours. Sometimes people need more than one operation, several months apart. The operation can take around 10 hours and your recovery can be slow. And you will need to take antibiotics for the rest of your life because of changes to your immune system. So you might need to have some vaccinations before, or just after, the operation. Some people need to have their spleen removed. the affected lining of your abdomen (peritoneum).the womb and ovaries if you are a woman.the fatty layers in the abdomen (the omentum).cancer attached to the surface of the liver.The operation varies between people, but can include removing: They then remove any tissues affected by PMP. The surgeon strips out the lining of the abdomen (the peritoneum). ![]() So there will be no cancer cells left that could start to grow again. The aim is to remove all of the visible PMP cells in your abdomen.
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